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Measuring Proviral HIV-1 DNA: Hurdles and Improvements to an Assay Monitoring Integration Events Utilising Human Alu Repeat Sequences
Integrated HIV-1 DNA persists despite antiretroviral therapy and can fuel viral rebound following treatment interruption. Hence, methods to specifically measure the integrated HIV-1 DNA portion only are important to monitor the reservoir in eradication trials. Here, we provide an up-to-date overview...
Autores principales: | Malatinkova, Eva, Thomas, Jordan, De Spiegelaere, Ward, Rutsaert, Sofie, Geretti, Anna Maria, Pollakis, Georgios, Paxton, William A., Vandekerckhove, Linos, Ruggiero, Alessandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706387/ https://www.ncbi.nlm.nih.gov/pubmed/34947941 http://dx.doi.org/10.3390/life11121410 |
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