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Prenatal Iron Deficiency and Choline Supplementation Interact to Epigenetically Regulate Jarid1b and Bdnf in the Rat Hippocampus into Adulthood

Early-life iron deficiency (ID) causes long-term neurocognitive impairments and gene dysregulation that can be partially mitigated by prenatal choline supplementation. The long-term gene dysregulation is hypothesized to underlie cognitive dysfunction. However, mechanisms by which iron and choline me...

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Detalles Bibliográficos
Autores principales: Liu, Shirelle X., Barks, Amanda K., Lunos, Scott, Gewirtz, Jonathan C., Georgieff, Michael K., Tran, Phu V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706459/
https://www.ncbi.nlm.nih.gov/pubmed/34960080
http://dx.doi.org/10.3390/nu13124527