Interdependent Regulation of Polycystin Expression Influences Starvation-Induced Autophagy and Cell Death

Autosomal dominant polycystic kidney disease (ADPKD) is mainly caused by deficiency of polycystin-1 (PC1) or polycystin-2 (PC2). Altered autophagy has recently been implicated in ADPKD progression, but its exact regulation by PC1 and PC2 remains unclear. We therefore investigated cell death and surv...

Descripción completa

Detalles Bibliográficos
Autores principales: Decuypere, Jean-Paul, Van Giel, Dorien, Janssens, Peter, Dong, Ke, Somlo, Stefan, Cai, Yiqiang, Mekahli, Djalila, Vennekens, Rudi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706473/
https://www.ncbi.nlm.nih.gov/pubmed/34948309
http://dx.doi.org/10.3390/ijms222413511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706473/
https://www.ncbi.nlm.nih.gov/pubmed/34948309
http://dx.doi.org/10.3390/ijms222413511

Ejemplares similares