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Melting and Re-Freezing Leads to Irreversible Changes in the Morphology and Molecular-Level Dynamics of Pfizer-BioNTech COVID-19 Vaccine

Background and Objectives: As an mRNA-based vaccine, the Pfizer-BioNTech COVID-19 vaccine has stringent cold storage requirements to preserve functionality of the mRNA active ingredient. To this end, lipid components of the vaccine formulation play an important role in stabilizing and protecting the...

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Detalles Bibliográficos
Autores principales: Mamontov, Eugene, Daemen, Luke L., Novak, Eric, Stone, Matthew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706477/
https://www.ncbi.nlm.nih.gov/pubmed/34946288
http://dx.doi.org/10.3390/medicina57121343