Plasma Metabolome Normalization in Rheumatoid Arthritis Following Initiation of Methotrexate and the Identification of Metabolic Biomarkers of Efficacy

Methotrexate (MTX) efficacy in the treatment of rheumatoid arthritis (RA) is variable and unpredictable, resulting in a need to identify biomarkers to guide drug therapy. This study evaluates changes in the plasma metabolome associated with response to MTX in RA with the goal of understanding the me...

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Detalles Bibliográficos
Autores principales: Medcalf, Matthew R., Bhadbhade, Pooja, Mikuls, Ted R., O’Dell, James R., Gundry, Rebekah L., Funk, Ryan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706490/
https://www.ncbi.nlm.nih.gov/pubmed/34940582
http://dx.doi.org/10.3390/metabo11120824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706490/
https://www.ncbi.nlm.nih.gov/pubmed/34940582
http://dx.doi.org/10.3390/metabo11120824

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