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Plasma Metabolome Normalization in Rheumatoid Arthritis Following Initiation of Methotrexate and the Identification of Metabolic Biomarkers of Efficacy
Methotrexate (MTX) efficacy in the treatment of rheumatoid arthritis (RA) is variable and unpredictable, resulting in a need to identify biomarkers to guide drug therapy. This study evaluates changes in the plasma metabolome associated with response to MTX in RA with the goal of understanding the me...
Autores principales: | Medcalf, Matthew R., Bhadbhade, Pooja, Mikuls, Ted R., O’Dell, James R., Gundry, Rebekah L., Funk, Ryan S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706490/ https://www.ncbi.nlm.nih.gov/pubmed/34940582 http://dx.doi.org/10.3390/metabo11120824 |
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