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Neuron-Derived Estrogen—A Key Neuromodulator in Synaptic Function and Memory

In addition to being a steroid hormone, 17β-estradiol (E(2)) is also a neurosteroid produced in neurons in various regions of the brain of many species, including humans. Neuron-derived E(2) (NDE(2)) is synthesized from androgen precursors via the action of the biosynthetic enzyme aromatase, which i...

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Detalles Bibliográficos
Autores principales: Brann, Darrell W., Lu, Yujiao, Wang, Jing, Sareddy, Gangadhara R., Pratap, Uday P., Zhang, Quanguang, Tekmal, Rajeshwar R., Vadlamudi, Ratna K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706511/
https://www.ncbi.nlm.nih.gov/pubmed/34948039
http://dx.doi.org/10.3390/ijms222413242