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Treatment of Erythroid Precursor Cells from β-Thalassemia Patients with Cinchona Alkaloids: Induction of Fetal Hemoglobin Production

β-thalassemias are among the most common inherited hemoglobinopathies worldwide and are the result of autosomal mutations in the gene encoding β-globin, causing an absence or low-level production of adult hemoglobin (HbA). Induction of fetal hemoglobin (HbF) is considered to be of key importance for...

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Detalles Bibliográficos
Autores principales: Zuccato, Cristina, Cosenza, Lucia Carmela, Zurlo, Matteo, Lampronti, Ilaria, Borgatti, Monica, Scapoli, Chiara, Gambari, Roberto, Finotti, Alessia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706579/
https://www.ncbi.nlm.nih.gov/pubmed/34948226
http://dx.doi.org/10.3390/ijms222413433