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Determination of Novel Anti-Cancer Agents by Targeting OGG1 Enzyme Using Integrated Bioinformatics Methods

The 8-oxoguanine DNA glycosylase (OGG1) enzyme is a key DNA glycosylase mediating the excision of 7,8-dihydro-8-oxoguanine (8-oxoG) from DNA molecule to the start base excision repair pathway. The OGG1 glycosylase function depletion has been seen to obstruct pathological conditions such as inflammat...

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Detalles Bibliográficos
Autores principales: Muhseen, Ziyad Tariq, Ali, Mustafa Hussein, Jaber, Nawar Rushdi, Mashrea, Dheyaa Shakir, Alfalki, Ali Mamoon, Li, Guanglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706639/
https://www.ncbi.nlm.nih.gov/pubmed/34948899
http://dx.doi.org/10.3390/ijerph182413290