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The Protective Mechanism of Deuterated Linoleic Acid Involves the Activation of the Ca(2+) Signaling System of Astrocytes in Ischemia In Vitro

Ischemia-like (oxygen-glucose deprivation, OGD) conditions followed by reoxygenation (OGD/R) cause massive death of cerebral cortex cells in culture as a result of the induction of necrosis and apoptosis. Cell death occurs as a result of an OGD-induced increase in Ca(2+) ions in the cytosol of neuro...

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Detalles Bibliográficos
Autores principales: Turovsky, Egor A., Varlamova, Elena G., Gudkov, Sergey V., Plotnikov, Egor Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706680/
https://www.ncbi.nlm.nih.gov/pubmed/34948013
http://dx.doi.org/10.3390/ijms222413216