The Role of Prostaglandin E1 as a Pain Mediator through Facilitation of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 2 via the EP2 Receptor in Trigeminal Ganglion Neurons of Mice

Cyclooxygenase metabolizes dihomo-γ-linolenic acid and arachidonic acid to form prostaglandin (PG) E, including PGE1 and PGE2, respectively. Although PGE2 is well known to play an important role in the development and maintenance of hyperalgesia and allodynia, the role of PGE1 in pain is unknown. We...

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Detalles Bibliográficos
Autores principales: Kwon, Jean, Choi, Young In, Jo, Hang Joon, Lee, Sang Hoon, Lee, Han Kyu, Kim, Heesoo, Moon, Jee Youn, Jung, Sung Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706703/
https://www.ncbi.nlm.nih.gov/pubmed/34948328
http://dx.doi.org/10.3390/ijms222413534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706703/
https://www.ncbi.nlm.nih.gov/pubmed/34948328
http://dx.doi.org/10.3390/ijms222413534

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