Cargando…

The Role of Prostaglandin E1 as a Pain Mediator through Facilitation of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 2 via the EP2 Receptor in Trigeminal Ganglion Neurons of Mice

Cyclooxygenase metabolizes dihomo-γ-linolenic acid and arachidonic acid to form prostaglandin (PG) E, including PGE1 and PGE2, respectively. Although PGE2 is well known to play an important role in the development and maintenance of hyperalgesia and allodynia, the role of PGE1 in pain is unknown. We...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kwon, Jean, Choi, Young In, Jo, Hang Joon, Lee, Sang Hoon, Lee, Han Kyu, Kim, Heesoo, Moon, Jee Youn, Jung, Sung Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706703/ https://www.ncbi.nlm.nih.gov/pubmed/34948328 http://dx.doi.org/10.3390/ijms222413534

Ejemplares similares

SUMOylation of the Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 2 Increases Surface Expression and the Maximal Conductance of the Hyperpolarization-Activated Current
por: Parker, Anna R., et al.
Publicado: (2017)

Critical role for hyperpolarization-activated cyclic nucleotide-gated channel 2 in the AIF-mediated apoptosis
por: Norberg, Erik, et al.
Publicado: (2010)

Dysfunctional Hyperpolarization-Activated Cyclic Nucleotide-gated Ion Channels in Cardiac Diseases
por: Zhao, Xiaoqi, et al.
Publicado: (2016)

Crizotinib inhibits hyperpolarization-activated cyclic nucleotide-gated channel 4 activity
por: Zhang, Zhushan, et al.
Publicado: (2017)

Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels: An Emerging Role in Neurodegenerative Diseases
por: Chang, Xiaoli, et al.
Publicado: (2019)

Computational Prediction of Phosphoinositide Binding to Hyperpolarization-Activated Cyclic-Nucleotide Gated Channels
por: Claveras Cabezudo, Ainara, et al.
Publicado: (2022)

Alterations in SUMOylation of the hyperpolarization‐activated cyclic nucleotide‐gated ion channel 2 during persistent inflammation
por: Forster, Lori A., et al.
Publicado: (2020)

Direct Regulation of Hyperpolarization-Activated Cyclic-Nucleotide Gated (HCN1) Channels by Cannabinoids
por: Mayar, Sultan, et al.
Publicado: (2022)

Differential expression of hyperpolarization-activated cyclic nucleotide-gated channel subunits during hippocampal development in the mouse
por: Seo, Hyunhyo, et al.
Publicado: (2015)

Repurposing hyperpolarization‐activated cyclic nucleotide‐gated channels as a novel therapy for breast cancer
por: Mok, Ka‐Chun, et al.
Publicado: (2021)

The HCN domain couples voltage gating and cAMP response in hyperpolarization-activated cyclic nucleotide-gated channels
por: Porro, Alessandro, et al.
Publicado: (2019)

Hyperpolarization‐activated cyclic nucleotide‐gated channels working as pacemaker channels in colonic interstitial cells of Cajal
por: Choi, Seok, et al.
Publicado: (2021)

Novel Potassium Channels in Kidney Mitochondria: The Hyperpolarization-Activated and Cyclic Nucleotide-Gated HCN Channels
por: León-Aparicio, Daniel, et al.
Publicado: (2019)

Bibliometric analysis of hyperpolarization-activated cyclic nucleotide-gated (HCN)channels research (2004-2020)
por: Tian, Chuanxi, et al.
Publicado: (2022)

Dexmedetomidine Inhibits Voltage-Gated Sodium Channels via α2-Adrenoceptors in Trigeminal Ganglion Neurons
por: Im, Sang-Taek, et al.
Publicado: (2018)

Hyperpolarization-activated and cyclic nucleotide-gated channels are differentially expressed in juxtaglomerular cells in the olfactory bulb of mice
por: Fried, Hans-Ulrich, et al.
Publicado: (2010)

Cation and voltage dependence of lidocaine inhibition of the hyperpolarization-activated cyclic nucleotide-gated HCN1 channel
por: Putrenko, Igor, et al.
Publicado: (2017)

The structure and function of TRIP8b, an auxiliary subunit of hyperpolarization-activated cyclic-nucleotide gated channels
por: Han, Ye, et al.
Publicado: (2020)

Structural and functional remodeling of the atrioventricular node with aging in rats: The role of hyperpolarization-activated cyclic nucleotide–gated and ryanodine 2 channels
por: Saeed, Yawer, et al.
Publicado: (2018)

Genetic variation in Hyperpolarization-activated cyclic nucleotide-gated channels and its relationship with neuroticism, cognition and risk of depression
por: McIntosh, Andrew M., et al.
Publicado: (2012)

Hyperpolarization‐Activated Cyclic Nucleotide‐Gated Channels and Ventricular Arrhythmias in Heart Failure: A Novel Target for Therapy?
por: Dias, Priyanthi, et al.
Publicado: (2013)

Decreased hyperpolarization-activated cyclic nucleotide-gated channels are involved in bladder dysfunction associated with spinal cord injury
por: Liu, Qian, et al.
Publicado: (2018)

Mechanical transduction of cytoplasmic-to-transmembrane-domain movements in a hyperpolarization-activated cyclic nucleotide–gated cation channel
por: Gross, Christine, et al.
Publicado: (2018)

The impact of hyperpolarization-activated cyclic nucleotide-gated (HCN) and voltage-gated potassium KCNQ/Kv7 channels on primary microglia function
por: Vay, Sabine Ulrike, et al.
Publicado: (2020)

A Novel Carbamoyloxy Arylalkanoyl Arylpiperazine Compound (SKL-NP) Inhibits Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channel Currents in Rat Dorsal Root Ganglion Neurons
por: Chung, Gehoon, et al.
Publicado: (2012)

Association between Reversal in the Expression of Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channel and Age-Related Atrial Fibrillation
por: Li, Yao-Dong, et al.
Publicado: (2014)

A synthetic peptide that prevents cAMP regulation in mammalian hyperpolarization-activated cyclic nucleotide-gated (HCN) channels
por: Saponaro, Andrea, et al.
Publicado: (2018)

ZD7288, a selective hyperpolarization-activated cyclic nucleotide-gated channel blocker, inhibits hippocampal synaptic plasticity
por: Zhang, Xiao-xue, et al.
Publicado: (2016)

Involvement of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 3 in Oxytocin Neuronal Activity in Lactating Rats With Pup Deprivation
por: Li, Dongyang, et al.
Publicado: (2020)

Pacemaking Activity in the Peripheral Nervous System: Physiology and Roles of Hyperpolarization Activated and Cyclic Nucleotide-Gated Channels in Neuropathic Pain
por: Liu, Fan, et al.
Publicado: (2020)

Muscle weakness and impaired motor coordination in hyperpolarization-activated cyclic nucleotide-gated potassium channel 1-deficient rats
por: Nishitani, Ai, et al.
Publicado: (2019)

The Hyperpolarization-Activated Cyclic-Nucleotide-Gated Channel Blocker Ivabradine Does Not Prevent Arrhythmias in Catecholaminergic Polymorphic Ventricular Tachycardia
por: Bueno-Levy, Hanna, et al.
Publicado: (2020)

Systemic administration of ivabradine, a hyperpolarization‐activated cyclic nucleotide‐gated channel inhibitor, blocks spontaneous absence seizures
por: Iacone, Yasmine, et al.
Publicado: (2021)

Retraction: A Novel Carbamoyloxy Arylalkanoyl Arylpiperazine Compound (SKL-NP) Inhibits Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channel Currents in Rat Dorsal Root Ganglion Neurons
por: Chung, Gehoon, et al.
Publicado: (2012)

THE DEPRESSION OF PHAGOCYTOSIS BY EXOGENOUS CYCLIC NUCLEOTIDES, PROSTAGLANDINS, AND THEOPHYLLINE
por: Cox, Joyce P., et al.
Publicado: (1973)

Hyperpolarization-Activated Cyclic Nucleotide-Gated Non-selective (HCN) Ion Channels Regulate Human and Murine Urinary Bladder Contractility
por: Mader, Felix, et al.
Publicado: (2018)

Hyperpolarization-Activated Cyclic Nucleotide-Gated Ion (HCN) Channels Regulate PC12 Cell Differentiation Toward Sympathetic Neuron
por: Zhong, Li-Ying, et al.
Publicado: (2019)

Attenuation of Native Hyperpolarization-Activated, Cyclic Nucleotide-Gated Channel Function by the Volatile Anesthetic Sevoflurane in Mouse Thalamocortical Relay Neurons
por: Schwerin, Stefan, et al.
Publicado: (2021)

TrkA inhibition alleviates bladder overactivity in cyclophosphamide-induced cystitis by targeting hyperpolarization-activated cyclic nucleotide-gated channels
por: Liu, Qian, et al.
Publicado: (2023)

The gating mechanism in cyclic nucleotide-gated ion channels
por: Mazzolini, Monica, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_o2ikqmks580pmq6bcntbpjp7oe