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Targeting DNA repair pathway in cancer: Mechanisms and clinical application

Over the last decades, the growing understanding on DNA damage response (DDR) pathways has broadened the therapeutic landscape in oncology. It is becoming increasingly clear that the genomic instability of cells resulted from deficient DNA damage response contributes to the occurrence of cancer. One...

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Detalles Bibliográficos
Autores principales: Wang, Manni, Chen, Siyuan, Ao, Danyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706759/
https://www.ncbi.nlm.nih.gov/pubmed/34977872
http://dx.doi.org/10.1002/mco2.103