Nano-Structured Lipid Carrier-Based Oral Glutathione Formulation Mediates Renoprotection against Cyclophosphamide-Induced Nephrotoxicity, and Improves Oral Bioavailability of Glutathione Confirmed through RP-HPLC Micellar Liquid Chromatography

The study aimed to develop a new glutathione (GSH) oral formulation to enhance the delivery of GSH and counter the nephrotoxicity of the anticancer drug, cyclophosphamide (CP). A nanostructured lipid carrier glutathione formulation (GSH-NLCs) composed of glutathione (500 mg), stearic and oleic acid...

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Detalles Bibliográficos
Autores principales: Ahmad, Adel M., Mohammed, Hamdoon A., Faris, Tarek M., Hassan, Abeer S., Mohamed, Hebatallah B., El Dosoky, Mahmoud I., Aboubakr, Esam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706828/
https://www.ncbi.nlm.nih.gov/pubmed/34946570
http://dx.doi.org/10.3390/molecules26247491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706828/
https://www.ncbi.nlm.nih.gov/pubmed/34946570
http://dx.doi.org/10.3390/molecules26247491

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