De Novo Molecular Design of Caspase-6 Inhibitors by a GRU-Based Recurrent Neural Network Combined with a Transfer Learning Approach

Due to their potential in the treatment of neurodegenerative diseases, caspase-6 inhibitors have attracted widespread attention. However, the existing caspase-6 inhibitors showed more or less inevitable deficiencies that restrict their clinical development and applications. Therefore, there is an ur...

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Detalles Bibliográficos
Autores principales: Huang, Shuheng, Mei, Hu, Lu, Laichun, Qiu, Minyao, Liang, Xiaoqi, Xu, Lei, Kuang, Zuyin, Heng, Yu, Pan, Xianchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706867/
https://www.ncbi.nlm.nih.gov/pubmed/34959651
http://dx.doi.org/10.3390/ph14121249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706867/
https://www.ncbi.nlm.nih.gov/pubmed/34959651
http://dx.doi.org/10.3390/ph14121249

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