Improvement of mRNA Delivery Efficiency to a T Cell Line by Modulating PEG-Lipid Content and Phospholipid Components of Lipid Nanoparticles

(1) Background: T cells are important target cells, since they exert direct cytotoxic effects on infected/malignant cells, and affect the regulatory functions of other immune cells in a target antigen-specific manner. One of the current approaches for modifying the function of T cells is gene transf...

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Detalles Bibliográficos
Autores principales: Tanaka, Hiroki, Miyama, Ryo, Sakurai, Yu, Tamagawa, Shinya, Nakai, Yuta, Tange, Kota, Yoshioka, Hiroki, Akita, Hidetaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706876/
https://www.ncbi.nlm.nih.gov/pubmed/34959378
http://dx.doi.org/10.3390/pharmaceutics13122097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706876/
https://www.ncbi.nlm.nih.gov/pubmed/34959378
http://dx.doi.org/10.3390/pharmaceutics13122097

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