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Insights into the Neutralization and DNA Binding of Toxin–Antitoxin System ParE(SO)-CopA(SO) by Structure-Function Studies

ParE(SO)-CopA(SO) is a new type II toxin–antitoxin (TA) system in prophage CP4So that plays an essential role in circular CP4So maintenance after the excision in Shewanella oneidensis. The toxin ParE(SO) severely inhibits cell growth, while CopA(SO) functions as an antitoxin to neutralize ParE(SO) t...

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Detalles Bibliográficos
Autores principales: Zhou, Juan, Du, Xue-Jian, Liu, Ying, Gao, Zeng-Qiang, Geng, Zhi, Dong, Yu-Hui, Zhang, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706911/
https://www.ncbi.nlm.nih.gov/pubmed/34946107
http://dx.doi.org/10.3390/microorganisms9122506