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A Cell Culture System to Investigate Marek’s Disease Virus Integration into Host Chromosomes

Marek’s disease virus (MDV) is a highly oncogenic alphaherpesvirus that causes a devastating neoplastic disease in chickens. MDV has been shown to integrate its genome into the telomeres of latently infected and tumor cells, which is crucial for efficient tumor formation. Telomeric repeat arrays pre...

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Detalles Bibliográficos
Autores principales: You, Yu, Vychodil, Tereza, Aimola, Giulia, Previdelli, Renato L., Göbel, Thomas W., Bertzbach, Luca D., Kaufer, Benedikt B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706938/
https://www.ncbi.nlm.nih.gov/pubmed/34946091
http://dx.doi.org/10.3390/microorganisms9122489