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Synthetic Methods for the Preparation of Conformationally Restricted Analogues of Nicotine
In the context of naturally occurring nitrogen heterocycles, nicotine is a chiral alkaloid present in tobacco plants, which can target and stimulate nicotinic acetylcholine receptors (nAChRs), a class of ligand-gated ion channels commonly located throughout the human brain. Due to its well-known tox...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706964/ https://www.ncbi.nlm.nih.gov/pubmed/34946630 http://dx.doi.org/10.3390/molecules26247544 |