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Structural Requirements in the Hemagglutinin Cleavage Site-Coding RNA Region for the Generation of Highly Pathogenic Avian Influenza Virus

Highly pathogenic avian influenza viruses (HPAIVs) with H5 and H7 hemagglutinin (HA) subtypes are derived from their low pathogenic counterparts following the acquisition of multiple basic amino acids in their HA cleavage site. It has been suggested that consecutive adenine residues and a stem-loop...

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Detalles Bibliográficos
Autores principales: Kida, Yurie, Okuya, Kosuke, Saito, Takeshi, Yamagishi, Junya, Ohnuma, Aiko, Hattori, Takanari, Miyamoto, Hiroko, Manzoor, Rashid, Yoshida, Reiko, Nao, Naganori, Kajihara, Masahiro, Watanabe, Tokiko, Takada, Ayato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707032/
https://www.ncbi.nlm.nih.gov/pubmed/34959552
http://dx.doi.org/10.3390/pathogens10121597