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Structural Requirements in the Hemagglutinin Cleavage Site-Coding RNA Region for the Generation of Highly Pathogenic Avian Influenza Virus
Highly pathogenic avian influenza viruses (HPAIVs) with H5 and H7 hemagglutinin (HA) subtypes are derived from their low pathogenic counterparts following the acquisition of multiple basic amino acids in their HA cleavage site. It has been suggested that consecutive adenine residues and a stem-loop...
Autores principales: | Kida, Yurie, Okuya, Kosuke, Saito, Takeshi, Yamagishi, Junya, Ohnuma, Aiko, Hattori, Takanari, Miyamoto, Hiroko, Manzoor, Rashid, Yoshida, Reiko, Nao, Naganori, Kajihara, Masahiro, Watanabe, Tokiko, Takada, Ayato |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707032/ https://www.ncbi.nlm.nih.gov/pubmed/34959552 http://dx.doi.org/10.3390/pathogens10121597 |
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