Defects in MMR Genes as a Seminal Example of Personalized Medicine: From Diagnosis to Therapy

Microsatellite instability (MSI) is the landmark feature of DNA mismatch repair deficiency, which can be found in 15–20% of all colorectal cancers (CRC). This specific set of tumors has been initially perceived as a niche for geneticists or gastroenterologists focused on inherited predispositions. H...

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Detalles Bibliográficos
Autores principales: Dal Buono, Arianna, Gaiani, Federica, Poliani, Laura, Correale, Carmen, Laghi, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707096/
https://www.ncbi.nlm.nih.gov/pubmed/34945805
http://dx.doi.org/10.3390/jpm11121333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707096/
https://www.ncbi.nlm.nih.gov/pubmed/34945805
http://dx.doi.org/10.3390/jpm11121333

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