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Defects in MMR Genes as a Seminal Example of Personalized Medicine: From Diagnosis to Therapy
Microsatellite instability (MSI) is the landmark feature of DNA mismatch repair deficiency, which can be found in 15–20% of all colorectal cancers (CRC). This specific set of tumors has been initially perceived as a niche for geneticists or gastroenterologists focused on inherited predispositions. H...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707096/ https://www.ncbi.nlm.nih.gov/pubmed/34945805 http://dx.doi.org/10.3390/jpm11121333 |