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Synthesis, Molecular Docking and Antiplasmodial Activities of New Tetrahydro-β-Carbolines

Malaria is still one of the most dangerous infectious diseases and the emergence of drug resistant parasites only worsens the situation. A series of new tetrahydro-β-carbolines were designed, synthesized by the Pictet–Spengler reaction, and characterized. Further, the compounds were screened for the...

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Detalles Bibliográficos
Autores principales: Jaromin, Anna, Gryzło, Beata, Jamrozik, Marek, Parapini, Silvia, Basilico, Nicoletta, Cegła, Marek, Taramelli, Donatella, Zagórska, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707145/
https://www.ncbi.nlm.nih.gov/pubmed/34948361
http://dx.doi.org/10.3390/ijms222413569