Mipsagargin: The Beginning—Not the End—of Thapsigargin Prodrug-Based Cancer Therapeutics

Søren Brøgger Christensen isolated and characterized the cell-penetrant sesquiterpene lactone Thapsigargin (TG) from the fruit Thapsia garganica. In the late 1980s/early 1990s, TG was supplied to multiple independent and collaborative groups. Using this TG, studies documented with a large variety of...

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Detalles Bibliográficos
Autores principales: Isaacs, John T., Brennen, William Nathaniel, Christensen, Søren Brøgger, Denmeade, Samuel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707208/
https://www.ncbi.nlm.nih.gov/pubmed/34946547
http://dx.doi.org/10.3390/molecules26247469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707208/
https://www.ncbi.nlm.nih.gov/pubmed/34946547
http://dx.doi.org/10.3390/molecules26247469

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