Opioid Receptors and Protonation-Coupled Binding of Opioid Drugs

Opioid receptors are G-protein-coupled receptors (GPCRs) part of cell signaling paths of direct interest to treat pain. Pain may associate with inflamed tissue characterized by acidic pH. The potentially low pH at tissue targeted by opioid drugs in pain management could impact drug binding to the op...

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Detalles Bibliográficos
Autores principales: Lešnik, Samo, Bertalan, Éva, Bren, Urban, Bondar, Ana-Nicoleta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707250/
https://www.ncbi.nlm.nih.gov/pubmed/34948150
http://dx.doi.org/10.3390/ijms222413353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707250/
https://www.ncbi.nlm.nih.gov/pubmed/34948150
http://dx.doi.org/10.3390/ijms222413353

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