In Situ Cell Signalling of the Hippo-YAP/TAZ Pathway in Reaction to Complex Dynamic Loading in an Intervertebral Disc Organ Culture

Recently, a dysregulation of the Hippo-YAP/TAZ pathway has been correlated with intervertebral disc (IVD) degeneration (IDD), as it plays a key role in cell survival, tissue regeneration, and mechanical stress. We aimed to investigate the influence of different mechanical loading regimes, i.e., unde...

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Detalles Bibliográficos
Autores principales: Croft, Andreas S., Roth, Ysaline, Oswald, Katharina A. C., Ćorluka, Slavko, Bermudez-Lekerika, Paola, Gantenbein, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707270/
https://www.ncbi.nlm.nih.gov/pubmed/34948441
http://dx.doi.org/10.3390/ijms222413641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707270/
https://www.ncbi.nlm.nih.gov/pubmed/34948441
http://dx.doi.org/10.3390/ijms222413641

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