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Genome Evolution from Random Ligation of RNAs of Autocatalytic Sets
The evolutionary origin of the genome remains elusive. Here, I hypothesize that its first iteration, the protogenome, was a multi-ribozyme RNA. It evolved, likely within liposomes (the protocells) forming in dry-wet cycling environments, through the random fusion of ribozymes by a ligase and was amp...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707343/ https://www.ncbi.nlm.nih.gov/pubmed/34948321 http://dx.doi.org/10.3390/ijms222413526 |