Circadian Clock Component BMAL1 in the Paraventricular Nucleus Regulates Glucose Metabolism

It is suggested that clock genes link the circadian rhythm to glucose and lipid metabolism. In this study, we explored the role of the clock gene Bmal1 in the hypothalamic paraventricular nucleus (PVN) in glucose metabolism. The Sim1-Cre-mediated deletion of Bmal1 markedly reduced insulin secretion,...

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Detalles Bibliográficos
Autores principales: Nakata, Masanori, Kumari, Parmila, Kita, Rika, Katsui, Nanako, Takeuchi, Yuriko, Kawaguchi, Tomoki, Yamazaki, Toshiya, Zhang, Boyang, Shimba, Shigeki, Yada, Toshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707417/
https://www.ncbi.nlm.nih.gov/pubmed/34960038
http://dx.doi.org/10.3390/nu13124487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707417/
https://www.ncbi.nlm.nih.gov/pubmed/34960038
http://dx.doi.org/10.3390/nu13124487

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