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Modeling of High-Density Compaction of Pharmaceutical Tablets Using Multi-Contact Discrete Element Method

The purpose of this work is to simulate the powder compaction of pharmaceutical materials at the microscopic scale in order to better understand the interplay of mechanical forces between particles, and to predict their compression profiles by controlling the microstructure. For this task, the new f...

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Detalles Bibliográficos
Autores principales: Giannis, Kostas, Schilde, Carsten, Finke, Jan Henrik, Kwade, Arno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707439/
https://www.ncbi.nlm.nih.gov/pubmed/34959475
http://dx.doi.org/10.3390/pharmaceutics13122194