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Pharmacological Inhibition of Sonic Hedgehog Signaling Suppresses Tumor Development in a Murine Model of Intrahepatic Cholangiocarcinoma

Cholangiocarcinoma (CCC) is the second most primary liver cancer with an aggressive biological behavior, and its incidence increases steadily. An aberrant up-regulation of the sonic hedgehog signaling pathway has been reported in a variety of hepatic diseases including hepatic inflammation, fibrosis...

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Detalles Bibliográficos
Autores principales: Cho, Kyungjoo, Moon, Hyuk, Seo, Sang Hyun, Ro, Simon Weonsang, Kim, Beom Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707521/
https://www.ncbi.nlm.nih.gov/pubmed/34948011
http://dx.doi.org/10.3390/ijms222413214