Improving Transungual Permeation Study Design by Increased Bovine Hoof Membrane Thickness and Subsequent Infection

Ungual formulations are regularly tested using human nails or animal surrogates in Franz diffusion cell experiments. Membranes sometimes less than 100 µm thick are used, disregarding the higher physiological thickness of human nails and possible fungal infection. In this study, bovine hoof membranes...

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Detalles Bibliográficos
Autores principales: Kappes, Sebastian, Faber, Thilo, Nelleßen, Lotta, Yesilkaya, Tanju, Bock, Udo, Lamprecht, Alf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707648/
https://www.ncbi.nlm.nih.gov/pubmed/34959379
http://dx.doi.org/10.3390/pharmaceutics13122098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707648/
https://www.ncbi.nlm.nih.gov/pubmed/34959379
http://dx.doi.org/10.3390/pharmaceutics13122098

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