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Intratracheally Inhalable Nifedipine-Loaded Chitosan-PLGA Nanocomposites as a Promising Nanoplatform for Lung Targeting: Snowballed Protection via Regulation of TGF-β/β-Catenin Pathway in Bleomycin-Induced Pulmonary Fibrosis

Pulmonary fibrosis is a serious ailment that may progress to lung remodeling and demolition, where the key participants in its incidence are fibroblasts responding to growth factors and cellular calcium swinging. Calcium channel blockers, like nifedipine (NFD), may represent auspicious agents in pul...

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Detalles Bibliográficos
Autores principales: Elkomy, Mohammed H., Khallaf, Rasha A., Mahmoud, Mohamed O., Hussein, Raghda R. S., El-Kalaawy, Asmaa M., Abdel-Razik, Abdel-Razik H., Aboud, Heba M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707652/
https://www.ncbi.nlm.nih.gov/pubmed/34959627
http://dx.doi.org/10.3390/ph14121225