Synthesis and Characterization of Andrographolide Derivatives as Regulators of βAPP Processing in Human Cells

Alzheimer’s disease (AD) is a devastating neurodegenerative disorder, one of the main characteristics of which is the abnormal accumulation of amyloid peptide (Aβ) in the brain. Whereas β-secretase supports Aβ formation along the amyloidogenic processing of the β-amyloid precursor protein (βAPP), α-...

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Detalles Bibliográficos
Autores principales: Dey, Arpita, Chen, Ran, Li, Feng, Maitra, Subhamita, Hernandez, Jean-Francois, Zhou, Guo-Chun, Vincent, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707718/
https://www.ncbi.nlm.nih.gov/pubmed/34946739
http://dx.doi.org/10.3390/molecules26247660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707718/
https://www.ncbi.nlm.nih.gov/pubmed/34946739
http://dx.doi.org/10.3390/molecules26247660

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