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Past and Future Strategies to Inhibit Membrane Localization of the KRAS Oncogene
KRAS is one of the most studied oncogenes. It is well known that KRAS undergoes post-translational modifications at its C-terminal end. These modifications are essential for its membrane location and activity. Despite significant efforts made in the past three decades to target the mechanisms involv...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707736/ https://www.ncbi.nlm.nih.gov/pubmed/34947990 http://dx.doi.org/10.3390/ijms222413193 |