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Evaluation of the Role of p53 Tumour Suppressor Posttranslational Modifications and TTC5 Cofactor in Lung Cancer

Mutations in the p53 tumor suppressor are found in over 50% of cancers. p53 function is controlled through posttranslational modifications and cofactor interactions. In this study, we investigated the posttranslationally modified p53, including p53 acetylated at lysine 382 (K382), p53 phosphorylated...

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Detalles Bibliográficos
Autores principales: Alhebshi, Hasen, Tian, Kun, Patnaik, Lipsita, Taylor, Rebecca, Bezecny, Pavel, Hall, Callum, Muller, Patricia Anthonia Johanna, Safari, Nazila, Creamer, Delta Patricia Menendez, Demonacos, Constantinos, Mutti, Luciano, Bittar, Mohamad Nidal, Krstic-Demonacos, Marija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707832/
https://www.ncbi.nlm.nih.gov/pubmed/34947995
http://dx.doi.org/10.3390/ijms222413198