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GSK3β Serine 389 Phosphorylation Modulates Cardiomyocyte Hypertrophy and Ischemic Injury

Prior studies show that glycogen synthase kinase 3β (GSK3β) contributes to cardiac ischemic injury and cardiac hypertrophy. GSK3β is constitutionally active and phosphorylation of GSK3β at serine 9 (S9) inactivates the kinase and promotes cellular growth. GSK3β is also phosphorylated at serine 389 (...

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Detalles Bibliográficos
Autores principales: Vainio, Laura, Taponen, Saija, Kinnunen, Sini M., Halmetoja, Eveliina, Szabo, Zoltan, Alakoski, Tarja, Ulvila, Johanna, Junttila, Juhani, Lakkisto, Päivi, Magga, Johanna, Kerkelä, Risto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707850/
https://www.ncbi.nlm.nih.gov/pubmed/34948382
http://dx.doi.org/10.3390/ijms222413586