Safety and Immunogenicity of M2-Deficient, Single Replication, Live Influenza Vaccine (M2SR) in Adults

M2SR (M2-deficient single replication) is an investigational live intranasal vaccine that protects against multiple influenza A subtypes in influenza-naïve and previously infected ferrets. We conducted a phase 1, first-in-human, randomized, dose-escalation, placebo-controlled study of M2SR safety an...

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Detalles Bibliográficos
Autores principales: Eiden, Joseph, Gordon, Gilad, Fierro, Carlos, Herber, Renee, Aitchison, Roger, Belshe, Robert, Greenberg, Harry, Hoft, Daniel, Hatta, Yasuko, Moser, Michael J., Tary-Lehmann, Magdalena, Kawaoka, Yoshihiro, Neumann, Gabriele, Radspinner, Paul, Bilsel, Pamuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707871/
https://www.ncbi.nlm.nih.gov/pubmed/34960134
http://dx.doi.org/10.3390/vaccines9121388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707871/
https://www.ncbi.nlm.nih.gov/pubmed/34960134
http://dx.doi.org/10.3390/vaccines9121388

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