Poly(C)-binding Protein 2 Regulates the p53 Expression via Interactions with the 5′-Terminal Region of p53 mRNA

The p53 protein is one of the major transcriptional factors which guards cell homeostasis. Here, we showed that poly(C)-binding protein 2 (PCBP2) can bind directly to the 5′ terminus of p53 mRNA by means of electrophoretic mobility shift assay. Binding sites of PCBP2 within this region of p53 mRNA w...

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Detalles Bibliográficos
Autores principales: Janecki, Damian M., Swiatkowska, Agata, Szpotkowska, Joanna, Urbanowicz, Anna, Kabacińska, Martyna, Szpotkowski, Kamil, Ciesiołka, Jerzy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708005/
https://www.ncbi.nlm.nih.gov/pubmed/34948101
http://dx.doi.org/10.3390/ijms222413306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708005/
https://www.ncbi.nlm.nih.gov/pubmed/34948101
http://dx.doi.org/10.3390/ijms222413306

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