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Salt-Sensitive Hypertension in GR(+/−) Rats Is Accompanied with Dysregulation in Adrenal Soluble Epoxide Hydrolase and Polyunsaturated Fatty Acid Pathways

Mutations within the glucocorticoid receptor (GR) gene locus lead to glucocorticoid resistance which is characterized by several clinical symptoms such as adrenal gland hyperplasia and salt-sensitive hypertension, although the underlying mechanisms are still unknown. We studied GR haploinsufficient...

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Detalles Bibliográficos
Autores principales: Vanderriele, Paul-Emmanuel, Wang, Qing, Mérillat, Anne-Marie, Ino, Frédérique, Aeschlimann, Gilles, Ehret, Xavier, Ancin Del Olmo, David, Ponce de León, Verónica, Scholl, Ute I., Winter, Denise V., Odermatt, Alex, Hummler, Edith, Verouti, Sophia N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708190/
https://www.ncbi.nlm.nih.gov/pubmed/34948014
http://dx.doi.org/10.3390/ijms222413218