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Novel Fluorinated Spermine and Small Molecule PEI to Deliver Anti-PD-L1 and Anti-VEGF siRNA for Highly Efficient Tumor Therapy

Small interfering RNA (siRNA) can specifically silence disease gene expression. This project investigated the overexpression of programmed death receptor ligand 1 (PD-L1) and vascular endothelial growth factor (VEGF) on the surface of tumor cells. However, the main obstacle to the development of gen...

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Detalles Bibliográficos
Autores principales: Zhang, Yihui, Yuan, Zihan, Jin, Yi, Zhang, Wenkai, Yuan, Wei-En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708240/
https://www.ncbi.nlm.nih.gov/pubmed/34959340
http://dx.doi.org/10.3390/pharmaceutics13122058