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Novel Fluorinated Spermine and Small Molecule PEI to Deliver Anti-PD-L1 and Anti-VEGF siRNA for Highly Efficient Tumor Therapy
Small interfering RNA (siRNA) can specifically silence disease gene expression. This project investigated the overexpression of programmed death receptor ligand 1 (PD-L1) and vascular endothelial growth factor (VEGF) on the surface of tumor cells. However, the main obstacle to the development of gen...
Autores principales: | Zhang, Yihui, Yuan, Zihan, Jin, Yi, Zhang, Wenkai, Yuan, Wei-En |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708240/ https://www.ncbi.nlm.nih.gov/pubmed/34959340 http://dx.doi.org/10.3390/pharmaceutics13122058 |
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