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In Silico Investigation of the Biological Implications of Complex DNA Damage with Emphasis in Cancer Radiotherapy through a Systems Biology Approach

Different types of DNA lesions forming in close vicinity, create clusters of damaged sites termed as “clustered/complex DNA damage” and they are considered to be a major challenge for DNA repair mechanisms resulting in significant repair delays and induction of genomic instability. Upon detection of...

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Detalles Bibliográficos
Autores principales: Pavlopoulou, Athanasia, Asfa, Seyedehsadaf, Gioukakis, Evangelos, Mavragani, Ifigeneia V., Nikitaki, Zacharenia, Takan, Işıl, Pouget, Jean-Pierre, Harrison, Lynn, Georgakilas, Alexandros G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708251/
https://www.ncbi.nlm.nih.gov/pubmed/34946681
http://dx.doi.org/10.3390/molecules26247602