Acetonitrile Adducts of Tranexamic Acid as Sensitive Ions for Quantification at Residue Levels in Human Plasma by UHPLC-MS/MS

The quantitative analysis of pharmaceuticals in biomatrices by liquid chromatography coupled with electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) is often hampered by adduct formation. The use of the molecular ion resulting from solvent adducts for quantification is uncommon, even if...

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Detalles Bibliográficos
Autores principales: Silva, Eduarda M. P., Barreiros, Luisa, Fernandes, Sara R., Sá, Paula, Ramalho, João P. Prates, Segundo, Marcela A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708297/
https://www.ncbi.nlm.nih.gov/pubmed/34959606
http://dx.doi.org/10.3390/ph14121205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708297/
https://www.ncbi.nlm.nih.gov/pubmed/34959606
http://dx.doi.org/10.3390/ph14121205

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