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Acetonitrile Adducts of Tranexamic Acid as Sensitive Ions for Quantification at Residue Levels in Human Plasma by UHPLC-MS/MS
The quantitative analysis of pharmaceuticals in biomatrices by liquid chromatography coupled with electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) is often hampered by adduct formation. The use of the molecular ion resulting from solvent adducts for quantification is uncommon, even if...
Autores principales: | Silva, Eduarda M. P., Barreiros, Luisa, Fernandes, Sara R., Sá, Paula, Ramalho, João P. Prates, Segundo, Marcela A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708297/ https://www.ncbi.nlm.nih.gov/pubmed/34959606 http://dx.doi.org/10.3390/ph14121205 |
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