Therapeutic Response of CCKBR-Positive Tumors to Combinatory Treatment with Everolimus and the Radiolabeled Minigastrin Analogue [(177)Lu]Lu-PP-F11N

The inhibition of the mammalian target of rapamycin complex 1 (mTORC1) by everolimus (RAD001) was recently shown to enhance the tumor uptake of radiolabeled minigastrin. In this paper, we investigate if this finding can improve the in vivo therapeutic response to [(177)Lu]Lu-PP-F11N treatment. The N...

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Detalles Bibliográficos
Autores principales: Grzmil, Michal, Imobersteg, Stefan, Blanc, Alain, Frank, Stephan, Schibli, Roger, Béhé, Martin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708304/
https://www.ncbi.nlm.nih.gov/pubmed/34959437
http://dx.doi.org/10.3390/pharmaceutics13122156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708304/
https://www.ncbi.nlm.nih.gov/pubmed/34959437
http://dx.doi.org/10.3390/pharmaceutics13122156

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