CK2 Phosphorylation Is Required for Regulation of Syntaxin 1A Activity in Ca(2+)-Triggered Release in Neuroendocrine Cells

The polybasic juxtamembrane region (5RK) of the plasma membrane neuronal SNARE, syntaxin1A (Syx), was previously shown by us to act as a fusion clamp in PC12 cells, as charge neutralization of 5RK promotes spontaneous and inhibits Ca(2+)-triggered release. Using a Syx-based FRET probe (CSYS), we dem...

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Detalles Bibliográficos
Autores principales: Barak-Broner, Noa, Singer-Lahat, Dafna, Chikvashvili, Dodo, Lotan, Ilana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708312/
https://www.ncbi.nlm.nih.gov/pubmed/34948351
http://dx.doi.org/10.3390/ijms222413556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708312/
https://www.ncbi.nlm.nih.gov/pubmed/34948351
http://dx.doi.org/10.3390/ijms222413556

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