Prediction of Blood-Brain Barrier Penetration (BBBP) Based on Molecular Descriptors of the Free-Form and In-Blood-Form Datasets

The blood-brain barrier (BBB) controls the entry of chemicals from the blood to the brain. Since brain drugs need to penetrate the BBB, rapid and reliable prediction of BBB penetration (BBBP) is helpful for drug development. In this study, free-form and in-blood-form datasets were prepared by modify...

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Detalles Bibliográficos
Autores principales: Sakiyama, Hiroshi, Fukuda, Motohisa, Okuno, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708321/
https://www.ncbi.nlm.nih.gov/pubmed/34946509
http://dx.doi.org/10.3390/molecules26247428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708321/
https://www.ncbi.nlm.nih.gov/pubmed/34946509
http://dx.doi.org/10.3390/molecules26247428

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