AXL Knock-Out in SNU475 Hepatocellular Carcinoma Cells Provides Evidence for Lethal Effect Associated with G2 Arrest and Polyploidization

AXL, a member of the TAM family, is a promising therapeutic target due to its elevated expression in advanced hepatocellular carcinoma (HCC), particularly in association with acquired drug resistance. Previously, RNA interference was used to study its role in cancer, and several phenotypic changes,...

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Detalles Bibliográficos
Autores principales: Batur, Tugce, Argundogan, Ayse, Keles, Umur, Mutlu, Zeynep, Alotaibi, Hani, Senturk, Serif, Ozturk, Mehmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708332/
https://www.ncbi.nlm.nih.gov/pubmed/34948046
http://dx.doi.org/10.3390/ijms222413247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708332/
https://www.ncbi.nlm.nih.gov/pubmed/34948046
http://dx.doi.org/10.3390/ijms222413247

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