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Fatty Acid Modification of the Anticancer Peptide LVTX-9 to Enhance Its Cytotoxicity against Malignant Melanoma Cells

Spider venom is a valuable resource for the development of novel anticancer drugs. In this study, we focused on novel linear amphipathic α-helical anticancer peptide LVTX-9, which was derived from the cDNA library of the venom gland of the spider Lycosa vittata. The cytotoxicity of LVTX-9 against mu...

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Detalles Bibliográficos
Autores principales: Li, Fengjiao, Wu, Saizhi, Chen, Ninglin, Zhu, Jingyu, Zhao, Xinxin, Zhang, Peng, Zeng, Youlin, Liu, Zhonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708390/
https://www.ncbi.nlm.nih.gov/pubmed/34941705
http://dx.doi.org/10.3390/toxins13120867